Speedy weight reduction with GLP‑1 medicines impacts extra than simply physique fats; it additionally reduces fat-free mass, together with muscle, bone, connective tissue, and fluids. Sometimes, about 75 % of weight reduction comes from fats, with roughly 25 % coming from fat-free mass, says Sriram Machineni, MD, an endocrinology, diabetes, and metabolism professional at Montefiore Well being System in New York Metropolis.
Menopause already will increase a lady’s danger of muscle loss (sarcopenia) and bone thinning (osteoporosis), so girls utilizing GLP‑1 medicines throughout this transition needs to be particularly vigilant. “Weight performs an amazing function in bone density,” says Chervenak. “Girls who lose giant quantities of weight are at an elevated danger for bone loss.”
Muscle loss can be a priority, significantly when bodily exercise is low, as there’s much less stimulus for muscle tissue to develop, says Dr. Machineni.
To reduce the dangers of bone and muscle loss, specialists beneficial specializing in each protein consumption and energy coaching.
